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Explore LibrarySouthern Comfort, often mistaken for a whiskey, is actually a whiskey-based liqueur created in 1874 by bartender Martin Wilkes Heron in New Orleans. Interestingly, the original recipe included whiskey, fruit, and spices, but the modern version doesn't necessarily contain any whiskey at all – instead, it's made with a neutral grain spirit base flavored to taste like whiskey, along with fruit and spice flavors.